diff --git a/CHANGELOG.md b/CHANGELOG.md
index 1a3fd6d6..28948fd6 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -4,6 +4,17 @@
 
 [1]: https://pypi.org/project/google-cloud-datastore/#history
 
+## [2.1.0](https://www.github.com/googleapis/python-datastore/compare/v2.0.1...v2.1.0) (2020-12-04)
+
+
+### Features
+
+* support autoconversion of Entity to Key for purposes of delete & delete_multi ([#123](https://www.github.com/googleapis/python-datastore/issues/123)) ([bf1dde6](https://www.github.com/googleapis/python-datastore/commit/bf1dde60b2f42e939c7dfa4a5228c3f41d565ece))
+
+### Fix
+
+* remove six dependency ([#120](https://www.github.com/googleapis/python-datastore/issues/120)) ([b1715e5](https://www.github.com/googleapis/python-datastore/commit/b1715e500f870fd5292bb84232b0039c2ac6be85))
+
 ### [2.0.1](https://www.github.com/googleapis/python-datastore/compare/v2.0.0...v2.0.1) (2020-11-13)
 
 
diff --git a/google/cloud/datastore/_gapic.py b/google/cloud/datastore/_gapic.py
index 3200ea3c..e901fe6c 100644
--- a/google/cloud/datastore/_gapic.py
+++ b/google/cloud/datastore/_gapic.py
@@ -15,7 +15,7 @@
 """Helpers for making API requests via gapic / gRPC."""
 
 from grpc import insecure_channel
-import six
+from urllib.parse import urlparse
 
 from google.cloud._helpers import make_secure_channel
 from google.cloud._http import DEFAULT_USER_AGENT
@@ -32,7 +32,7 @@ def make_datastore_api(client):
     :rtype: :class:`.datastore.v1.datastore_client.DatastoreClient`
     :returns: A datastore API instance with the proper credentials.
     """
-    parse_result = six.moves.urllib_parse.urlparse(client._base_url)
+    parse_result = urlparse(client._base_url)
     host = parse_result.netloc
     if parse_result.scheme == "https":
         channel = make_secure_channel(client._credentials, DEFAULT_USER_AGENT, host)
diff --git a/google/cloud/datastore/client.py b/google/cloud/datastore/client.py
index 24b53b54..28d968ce 100644
--- a/google/cloud/datastore/client.py
+++ b/google/cloud/datastore/client.py
@@ -622,7 +622,8 @@ def delete(self, key, retry=None, timeout=None):
            The backend API does not make a distinction between a single key or
            multiple keys in a commit request.
 
-        :type key: :class:`google.cloud.datastore.key.Key`
+        :type key: :class:`google.cloud.datastore.key.Key`, :class:`google.cloud.datastore.entity.Entity`
+
         :param key: The key to be deleted from the datastore.
 
         :type retry: :class:`google.api_core.retry.Retry`
@@ -643,7 +644,7 @@ def delete(self, key, retry=None, timeout=None):
     def delete_multi(self, keys, retry=None, timeout=None):
         """Delete keys from the Cloud Datastore.
 
-        :type keys: list of :class:`google.cloud.datastore.key.Key`
+        :type keys: list of :class:`google.cloud.datastore.key.Key`, :class:`google.cloud.datastore.entity.Entity`
         :param keys: The keys to be deleted from the Datastore.
 
         :type retry: :class:`google.api_core.retry.Retry`
@@ -671,6 +672,9 @@ def delete_multi(self, keys, retry=None, timeout=None):
             current.begin()
 
         for key in keys:
+            if isinstance(key, Entity):
+                # If the key is in fact an Entity, the key can be extracted.
+                key = key.key
             current.delete(key)
 
         if not in_batch:
diff --git a/google/cloud/datastore/helpers.py b/google/cloud/datastore/helpers.py
index f8b32f38..eada5f4f 100644
--- a/google/cloud/datastore/helpers.py
+++ b/google/cloud/datastore/helpers.py
@@ -22,7 +22,6 @@
 
 from google.protobuf import struct_pb2
 from google.type import latlng_pb2
-import six
 
 from google.cloud._helpers import _datetime_to_pb_timestamp
 from google.cloud.datastore_v1.types import datastore as datastore_pb2
@@ -105,7 +104,7 @@ def _property_tuples(entity_pb):
     :returns: An iterator that yields tuples of a name and ``Value``
               corresponding to properties on the entity.
     """
-    return six.iteritems(entity_pb.properties)
+    return iter(entity_pb.properties.items())
 
 
 def entity_from_protobuf(pb):
@@ -206,7 +205,7 @@ def _set_pb_meaning_from_entity(entity, name, value, value_pb, is_list=False):
     if is_list:
         if not isinstance(meaning, list):
             meaning = itertools.repeat(meaning)
-        val_iter = six.moves.zip(value_pb.array_value.values, meaning)
+        val_iter = zip(value_pb.array_value.values, meaning)
         for sub_value_pb, sub_meaning in val_iter:
             if sub_meaning is not None:
                 sub_value_pb.meaning = sub_meaning
@@ -359,11 +358,11 @@ def _pb_attr_value(val):
         name, value = "boolean", val
     elif isinstance(val, float):
         name, value = "double", val
-    elif isinstance(val, six.integer_types):
+    elif isinstance(val, int):
         name, value = "integer", val
-    elif isinstance(val, six.text_type):
+    elif isinstance(val, str):
         name, value = "string", val
-    elif isinstance(val, six.binary_type):
+    elif isinstance(val, bytes):
         name, value = "blob", val
     elif isinstance(val, Entity):
         name, value = "entity", val
diff --git a/google/cloud/datastore/key.py b/google/cloud/datastore/key.py
index c9beaeb2..98502f9c 100644
--- a/google/cloud/datastore/key.py
+++ b/google/cloud/datastore/key.py
@@ -16,7 +16,6 @@
 
 import base64
 import copy
-import six
 
 from google.cloud.datastore_v1.types import entity as _entity_pb2
 
@@ -185,14 +184,14 @@ def _parse_path(path_args):
         result = []
         for kind, id_or_name in zip(kind_list, id_or_name_list):
             curr_key_part = {}
-            if isinstance(kind, six.string_types):
+            if isinstance(kind, str):
                 curr_key_part["kind"] = kind
             else:
                 raise ValueError(kind, "Kind was not a string.")
 
-            if isinstance(id_or_name, six.string_types):
+            if isinstance(id_or_name, str):
                 curr_key_part["name"] = id_or_name
-            elif isinstance(id_or_name, six.integer_types):
+            elif isinstance(id_or_name, int):
                 curr_key_part["id"] = id_or_name
             elif id_or_name is not partial_ending:
                 raise ValueError(id_or_name, "ID/name was not a string or integer.")
@@ -264,9 +263,9 @@ def completed_key(self, id_or_name):
         if not self.is_partial:
             raise ValueError("Only a partial key can be completed.")
 
-        if isinstance(id_or_name, six.string_types):
+        if isinstance(id_or_name, str):
             id_or_name_key = "name"
-        elif isinstance(id_or_name, six.integer_types):
+        elif isinstance(id_or_name, int):
             id_or_name_key = "id"
         else:
             raise ValueError(id_or_name, "ID/name was not a string or integer.")
diff --git a/google/cloud/datastore/version.py b/google/cloud/datastore/version.py
index 956a957b..8b5d3328 100644
--- a/google/cloud/datastore/version.py
+++ b/google/cloud/datastore/version.py
@@ -12,4 +12,4 @@
 # See the License for the specific language governing permissions and
 # limitations under the License.
 
-__version__ = "2.0.1"
+__version__ = "2.1.0"
diff --git a/tests/system/test_system.py b/tests/system/test_system.py
index c807781b..a91b99ae 100644
--- a/tests/system/test_system.py
+++ b/tests/system/test_system.py
@@ -18,7 +18,6 @@
 import warnings
 
 import requests
-import six
 
 from google.cloud._helpers import UTC
 from google.cloud import datastore
@@ -73,9 +72,8 @@ def setUpModule():
 
 
 def tearDownModule():
-    keys = [entity.key for entity in Config.TO_DELETE]
     with Config.CLIENT.transaction():
-        Config.CLIENT.delete_multi(keys)
+        Config.CLIENT.delete_multi(Config.TO_DELETE)
 
 
 class TestDatastore(unittest.TestCase):
@@ -84,8 +82,7 @@ def setUp(self):
 
     def tearDown(self):
         with Config.CLIENT.transaction():
-            keys = [entity.key for entity in self.case_entities_to_delete]
-            Config.CLIENT.delete_multi(keys)
+            Config.CLIENT.delete_multi(self.case_entities_to_delete)
 
 
 class TestDatastoreAllocateIDs(TestDatastore):
@@ -294,7 +291,7 @@ def test_limit_queries(self):
 
         # Fetch characters.
         iterator = query.fetch(limit=limit)
-        page = six.next(iterator.pages)
+        page = next(iterator.pages)
         character_entities = list(page)
         cursor = iterator.next_page_token
         self.assertEqual(len(character_entities), limit)
@@ -442,7 +439,7 @@ def test_query_paginate_with_offset(self):
         iterator = page_query.fetch(limit=limit, offset=offset)
 
         # Fetch characters.
-        page = six.next(iterator.pages)
+        page = next(iterator.pages)
         entities = list(page)
         cursor = iterator.next_page_token
         self.assertEqual(len(entities), limit)
@@ -466,7 +463,7 @@ def test_query_paginate_with_start_cursor(self):
         iterator = page_query.fetch(limit=limit, offset=offset)
 
         # Fetch characters.
-        page = six.next(iterator.pages)
+        page = next(iterator.pages)
         entities = list(page)
         cursor = iterator.next_page_token
         self.assertEqual(len(entities), limit)
diff --git a/tests/system/utils/clear_datastore.py b/tests/system/utils/clear_datastore.py
index 3438ff89..fa976f60 100644
--- a/tests/system/utils/clear_datastore.py
+++ b/tests/system/utils/clear_datastore.py
@@ -19,8 +19,6 @@
 import os
 import sys
 
-import six
-
 from google.cloud import datastore
 
 
@@ -96,7 +94,7 @@ def main():
 
     print_func("This command will remove all entities for " "the following kinds:")
     print_func("\n".join("- " + val for val in kinds))
-    response = six.moves.input("Is this OK [y/n]? ")
+    response = input("Is this OK [y/n]? ")
 
     if response.lower() == "y":
 
diff --git a/tests/system/utils/populate_datastore.py b/tests/system/utils/populate_datastore.py
index 223741e8..06b2895a 100644
--- a/tests/system/utils/populate_datastore.py
+++ b/tests/system/utils/populate_datastore.py
@@ -23,8 +23,6 @@
 import time
 import uuid
 
-import six
-
 from google.cloud import datastore
 
 
@@ -121,7 +119,7 @@ def add_characters(client=None):
         # Get a client that uses the test dataset.
         client = datastore.Client()
     with client.transaction() as xact:
-        for key_path, character in six.moves.zip(KEY_PATHS, CHARACTERS):
+        for key_path, character in zip(KEY_PATHS, CHARACTERS):
             if key_path[-1] != character["name"]:
                 raise ValueError(("Character and key don't agree", key_path, character))
             entity = datastore.Entity(key=client.key(*key_path))
diff --git a/tests/unit/test__http.py b/tests/unit/test__http.py
index 700429ff..6048d40b 100644
--- a/tests/unit/test__http.py
+++ b/tests/unit/test__http.py
@@ -15,7 +15,7 @@
 import unittest
 
 import mock
-from six.moves import http_client
+from http import client
 
 import requests
 
@@ -72,7 +72,7 @@ def test_failure(self):
         error.code = code_pb2.FAILED_PRECONDITION
 
         http = _make_requests_session(
-            [_make_response(http_client.BAD_REQUEST, content=error.SerializeToString())]
+            [_make_response(client.BAD_REQUEST, content=error.SerializeToString())]
         )
 
         with self.assertRaises(BadRequest) as exc:
@@ -808,7 +808,7 @@ def test_allocate_ids_non_empty(self):
             self.assertEqual(key_before, key_after)
 
 
-def _make_response(status=http_client.OK, content=b"", headers={}):
+def _make_response(status=client.OK, content=b"", headers={}):
     response = requests.Response()
     response.status_code = status
     response._content = content
diff --git a/tests/unit/test_client.py b/tests/unit/test_client.py
index 55a45c7f..3c75a5fb 100644
--- a/tests/unit/test_client.py
+++ b/tests/unit/test_client.py
@@ -961,6 +961,24 @@ def test_delete_multi_w_existing_transaction(self):
         self.assertEqual(mutated_key, key._key)
         client._datastore_api_internal.commit.assert_not_called()
 
+    def test_delete_multi_w_existing_transaction_entity(self):
+        from google.cloud.datastore.entity import Entity
+
+        creds = _make_credentials()
+        client = self._make_one(credentials=creds)
+        client._datastore_api_internal = _make_datastore_api()
+
+        key = _Key()
+        entity = Entity(key=key)
+
+        with _NoCommitTransaction(client) as CURR_XACT:
+            result = client.delete_multi([entity])
+
+        self.assertIsNone(result)
+        mutated_key = _mutated_pb(self, CURR_XACT.mutations, "delete")
+        self.assertEqual(mutated_key, key._key)
+        client._datastore_api_internal.commit.assert_not_called()
+
     def test_allocate_ids_w_partial_key(self):
         num_ids = 2